The fifth edition of the Manual of Allergy and Immunology is designed to serve health care professionals in the diagnosis and management of allergic and other immunological disorders. The manual presents the basic and essential material and provides specific information to assist in clinical decision-making and treatment planning. The specialist will find this manual a convenient reference handbook, while the generalist will be able to use the Manual as a helpful guide in formulating a diagnostic and therapeutic approach to patients suspected of having an allergic or immunologic disorder. Students, house officers, and other health care professionals will find the Manual a useful guide to the clinical practice of allergy and immunology.