This book is designed to impart the knowledge on Parkinson content and recent experimental techniques in the drug discovery and development. The book content helps the student to understand the etiology, pathophysiology, diagnosis and treatment and basic knowledge of various in-vitro preclinical evaluation processes. Upon completion of the course the student shall be able to, Discuss the pathophysiology and pharmacotherapy of Parkinson Disease. Explain the mechanism of drug actions at cellular and molecular level Describe the various newer screening methods involved in the Parkinson disease Appreciate and correlate the preclinical data to humans.